Research Output 1997 2018

2018

Author Correction: Stem cells from human apical papilla decrease neuro‑inflammation and stimulate oligodendrocyte progenitor differentiation via activin‑A secretion

de Berdt, P., Bottemanne, P., Bianco, J., Alhouayek, M., Diogenes, A., Lloyd, A., Gerardo-Nava, J., Brook, G. A., Miron, V., Muccioli, G. G. & Rieux, A. D. Mar 22 2018 (Accepted/In press) In : Cellular and Molecular Life Sciences. 1 p.

Research output: Contribution to journalArticle

Oligodendroglia
Names
Publications
Stem Cells
Inflammation

Effect of 3 Bioceramic Materials on Stem Cells of the Apical Papilla Proliferation and Differentiation Using a Dentin Disk Model

Miller, A. A., Takimoto, K., Wealleans, J. & Diogenes, A. Apr 1 2018 In : Journal of endodontics. 44, 4, p. 599-603 5 p.

Research output: Contribution to journalArticle

Dentin
Stem Cells
Dental Specialties
Staining and Labeling
Saints

Stem cells from human apical papilla decrease neuro-inflammation and stimulate oligodendrocyte progenitor differentiation via activin-A secretion

de Berdt, P., Bottemanne, P., Bianco, J., Alhouayek, M., Diogenes, A., Llyod, A., Gerardo-Nava, J., Brook, G. A., Miron, V., Muccioli, G. G. & Rieux, A. D. Feb 7 2018 (Accepted/In press) In : Cellular and Molecular Life Sciences. p. 1-14 14 p.

Research output: Contribution to journalArticle

Oligodendroglia
Stem Cells
Inflammation
Spinal Cord
Spinal Cord Injuries
2017
1 Citations

A-kinase anchoring protein 79/150 scaffolds transient receptor potential a 1 phosphorylation and sensitization by metabotropic glutamate receptor activation

Brackley, A. D., Gomez, R., Guerrero, K. A., Akopian, A. N., Glucksman, M. J., Du, J., Carlton, S. M. & Jeske, N. A. Dec 1 2017 In : Scientific Reports. 7, 1, 1842

Research output: Contribution to journalArticle

Metabotropic Glutamate Receptors
Protein Kinases
Hypersensitivity
Phosphorylation
Sensory Receptor Cells

Comparative Evaluation of Chemotactic Factor Effect on Migration and Differentiation of Stem Cells of the Apical Papilla

Fayazi, S., Takimoto, K. & Diogenes, A. Aug 1 2017 In : Journal of Endodontics. 43, 8, p. 1288-1293 6 p.

Research output: Contribution to journalArticle

Chemotactic Factors
Stem Cells
Granulocyte Colony-Stimulating Factor
Endodontics
Fibroblast Growth Factor 2
3 Citations

Decellularized Human Dental Pulp as a Scaffold for Regenerative Endodontics

Song, J. S., Takimoto, K., Jeon, M., Vadakekalam, J., Ruparel, N. B. & Diogenes, A. Jun 1 2017 In : Journal of Dental Research. 96, 6, p. 640-646 7 p.

Research output: Contribution to journalArticle

Dental Pulp
Endodontics
Tooth
Stem Cells
Dental Pulp Cavity
2 Citations

Effect of Bacterial Biofilm on the Osteogenic Differentiation of Stem Cells of Apical Papilla

Vishwanat, L., Duong, R., Takimoto, K., Phillips, L., Espitia, C. O., Diogenes, A., Ruparel, S. B., Kolodrubetz, D. & Ruparel, N. B. Jun 1 2017 In : Journal of Endodontics. 43, 6, p. 916-922 7 p.

Research output: Contribution to journalArticle

Biofilms
Stem Cells
Enterococcus faecalis
Endodontics
Dental Pulp Cavity
2 Citations
Dental Pulp
Hydrogel
Hyaluronic Acid
Regeneration
Endodontics

Evaluation of mesenchymal stem cell modulation of trigeminal neuronal responses to cold

Eskander, M. A., Takimoto, K. & Diogenes, A. Sep 30 2017 In : Neuroscience. 360, p. 61-67 7 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Stem Cells
Coculture Techniques
Endodontics
Ion Channels
3 Citations

Extracellular matrix-derived hydrogels for dental stem cell delivery

Viswanath, A., Vanacker, J., Germain, L., Leprince, J. G., Diogenes, A., Shakesheff, K. M., White, L. J. & des Rieux, A. Jan 1 2017 In : Journal of Biomedical Materials Research - Part A. 105, 1, p. 319-328 10 p.

Research output: Contribution to journalArticle

Hydrogels
Stem cells
Extracellular Matrix
Tooth
Stem Cells
1 Citations

Histologic Evaluation of Regenerative Endodontic Procedures with the Use of Chitosan Scaffolds in Immature Dog Teeth with Apical Periodontitis

Palma, P. J., Ramos, J. C., Martins, J. B., Diogenes, A., Figueiredo, M. H., Ferreira, P., Viegas, C. & Santos, J. M. Aug 1 2017 In : Journal of Endodontics. 43, 8, p. 1279-1287 9 p.

Research output: Contribution to journalArticle

Periapical Periodontitis
Endodontics
Chitosan
Tooth
Dental Pulp Cavity

Microbial Modulation of Stem Cells and Future Directions in Regenerative Endodontics

Diogenes, A. & Hargreaves, K. M. Sep 1 2017 In : Journal of Endodontics. 43, 9, p. S95-S101

Research output: Contribution to journalArticle

Endodontics
Stem Cells
Dental Pulp Cavity
Dentin
Tooth
2 Citations

Regenerative Endodontic Procedures: Clinical Outcomes

Diogenes, A. & Ruparel, N. B. Jan 1 2017 In : Dental Clinics of North America. 61, 1, p. 111-125 15 p.

Research output: Contribution to journalReview article

Endodontics
Dentin
Dental Pulp Necrosis
Tooth
Research
4 Citations

Survival of the Apical Papilla and Its Resident Stem Cells in a Case of Advanced Pulpal Necrosis and Apical Periodontitis

Chrepa, V., Pitcher, B., Henry, M. A. & Diogenes, A. Apr 1 2017 In : Journal of Endodontics. 43, 4, p. 561-567 7 p.

Research output: Contribution to journalArticle

Periapical Periodontitis
Necrosis
Stem Cells
Survival
Dental Pulp Necrosis
4 Citations

The TRPA1 ion channel is expressed in CD4+ t cells and restrains T-cell-mediated colitis through inhibition of TRPV1

Bertin, S., Aoki-Nonaka, Y., Lee, J., De Jong, P. R., Kim, P., Han, T., Yu, T., To, K., Takahashi, N., Boland, B. S., Chang, J. T., Ho, S. B., Herdman, S., Corr, M., Franco, A., Sharma, S., Dong, H., Akopian, A. N. & Raz, E. Jan 1 2017 In : Gut. 66, 9, p. 1584-1596 13 p.

Research output: Contribution to journalArticle

Ankyrins
Colitis
Ion Channels
T-Lymphocytes
vanilloid receptor subtype 1

TrpA1 activation in peripheral sensory neurons underlies the ionic basis of pain hypersensitivity in response to vinca alkaloids

Boiko, N., Medrano, G., Montano, E., Jiang, N., Williams, C. R., Madungwe, N. B., Bopassa, J. C., Kim, C. C., Parrish, J. Z., Hargreaves, K. M., Stockand, J. D. & Eaton, B. A. Oct 1 2017 In : PLoS ONE. 12, 10, e0186888

Research output: Contribution to journalArticle

Vinca
Ankyrins
Vinca Alkaloids
ankyrins
Chemotherapy
2016
1 Citations

Adding Regenerative Endodontics to the Table of Contents

Hargreaves, K. M. Jan 1 2016 In : Journal of Endodontics. 42, 1, p. 1 1 p.

Research output: Contribution to journalArticle

Editorial Policies
Endodontics
3 Citations

BDNF signaling contributes to oral cancer pain in a preclinical orthotopic rodent model

Chodroff, L., Bendele, M., Valenzuela, V., Henry, M. & Ruparel, S. Sep 1 2016 In : Molecular Pain. 12

Research output: Contribution to journalArticle

Mouth Neoplasms
Brain-Derived Neurotrophic Factor
Rodentia
Pain
Squamous Cell Carcinoma

Capsaicin-sensitive Innervation Modulates the Development of Apical Periodontitis

Austah, O. N., Ruparel, N. B., Henry, M. A., Fajardo, R. J., Schmitz, J. E. & Diogenes, A. Oct 1 2016 In : Journal of Endodontics. 42, 10, p. 1496-1502 7 p.

Research output: Contribution to journalArticle

Periapical Periodontitis
Capsaicin
Calcitonin Gene-Related Peptide
Neurons
Dental Pulp
3 Citations
Hyperalgesia
Lipids
Spinal Injections
Spinal Cord
Wounds and Injuries

Clinical strategies for dental and periodontal disease management: A way forward

Diogenes, A., Chrepa, V. & Ruparel, N. B. Nov 1 2016 Tissue Engineering and Regeneration in Dentistry: Current Strategies. Wiley Blackwell, p. 145-168 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Stomatognathic Diseases
Periodontal Diseases
Disease Management
Guided Tissue Regeneration
Regeneration
1 Citations

EphrinB2 Stabilizes Vascularlike Structures Generated by Endothelial Cells and Stem Cells from Apical Papilla

Yuan, C., Wang, P., Zhu, S., Zou, T., Wang, S., Xu, J., Heng, B. C., Diogenes, A. & Zhang, C. 2016 (Accepted/In press) In : Journal of Endodontics.

Research output: Contribution to journalArticle

Human Umbilical Vein Endothelial Cells
Stem Cells
Endothelial Cells
Coculture Techniques
Phosphorylation
4 Citations

GRK2 Constitutively Governs Peripheral Delta Opioid Receptor Activity

Brackley, A. D., Gomez, R., Akopian, A. N., Henry, M. A. & Jeske, N. A. Sep 1 2016 In : Cell Reports. 16, 10, p. 2686-2698 13 p.

Research output: Contribution to journalArticle

G-Protein-Coupled Receptor Kinase 2
delta Opioid Receptor
raf Kinases
Opioid Analgesics
Analgesics
4 Citations

Influence of Age and Apical Diameter on the Success of Endodontic Regeneration Procedures

Estefan, B. S., El Batouty, K. M., Nagy, M. M. & Diogenes, A. Nov 1 2016 In : Journal of Endodontics. 42, 11, p. 1620-1625 6 p.

Research output: Contribution to journalArticle

Endodontics
Regeneration
Tooth
Age Groups
Incisor
1 Citations

Oscillating from Neurosecretion to Multitasking Dopamine Neurons

Grattan, D. R. & Akopian, A. N. Apr 26 2016 In : Cell Reports. 15, 4, p. 681-682 2 p.

Research output: Contribution to journalArticle

Neurosecretion
Multitasking
Dopaminergic Neurons
Neurons
Dopamine
4 Citations

Role of Oxidized Lipids and TRP Channels in Orofacial Pain and Inflammation

Dubner, R., Hargreaves, K. M. & Ruparel, S. Sep 1 2016 In : Journal of Dental Research. 95, 10, p. 1117-1123 7 p.

Research output: Contribution to journalReview article

Facial Pain
Linoleic Acid
Inflammation
Lipids
Arachidonic Acid
6 Citations

TRP channels and traffic-related environmental pollution-induced pulmonary disease

Akopian, A. N., Fanick, E. R. & Brooks, E. G. May 1 2016 In : Seminars in Immunopathology. 38, 3, p. 331-338 8 p.

Research output: Contribution to journalArticle

Transient Receptor Potential Channels
Vehicle Emissions
Environmental Pollution
Lung Diseases
Particulate Matter
2015

Advances in the dental and surgical management of orofacial pain

Palla, S., Hargreaves, K. M., Winocur, E. & Palla, A. Jun 1 2015 Orofacial Pain. Wolters Kluwer Health Adis (ESP)

Research output: Chapter in Book/Report/Conference proceedingChapter

Stomatognathic System
Facial Pain
Tooth
Referred Pain
Pain
25 Citations

Delivery of apical mesenchymal stem cells into root canals of mature teeth

Chrepa, V., Henry, M. A., Daniel, B. J. & Diogenes, A. Dec 1 2015 In : Journal of Dental Research. 94, 12, p. 1653-1659 7 p.

Research output: Contribution to journalArticle

Dental Pulp Cavity
Mesenchymal Stromal Cells
Tooth
Endodontics
Periapical Tissue
12 Citations

Dental apical papilla as therapy for spinal cord injury

De Berdt, P., Vanacker, J., Ucakar, B., Elens, L., Diogenes, A., Leprince, J. G., Deumens, R. & Des Rieux, A. Nov 1 2015 In : Journal of Dental Research. 94, 11, p. 1575-1581 7 p.

Research output: Contribution to journalArticle

Dental Papilla
Spinal Cord Injuries
Hydrogel
Stem Cells
Transplantation
4 Citations

Effect of a novel, orally active matrix metalloproteinase-2 and -9 inhibitor in spinal and trigeminal rat models of neuropathic pain

Henry, M. A., Fairchild, D. D., Patil, M. J., Hanania, T., Hain, H. S., Davis, S. F., Malekiani, S. A., Hu, A., Sucholeiki, R., Nix, D. & Sucholeiki, I. 2015 In : Journal of Oral and Facial Pain and Headache. 29, 3, p. 286-296 11 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 2
Matrix Metalloproteinase 9
Neuralgia
Hyperalgesia
Constriction
9 Citations

Fibrin hydrogels to deliver dental stem cells of the apical papilla for regenerative medicine

Germain, L., De Berdt, P., Vanacker, J., Leprince, J., Diogenes, A., Jacobs, D., Vandermeulen, G., Bouzin, C., Préat, V., Dupont-Gillain, C. & Des Rieux, A. Mar 1 2015 In : Regenerative Medicine. 10, 2, p. 153-167 15 p.

Research output: Contribution to journalArticle

Hydrogels
Regenerative Medicine
Stem cells
Fibrin
Tooth

Inflammatory and cancer-related orofacial pain mechanisms: Insights from human experimental studies

Ernberg, M., Hargreaves, K. & Schmidt, B. Jun 1 2015 Orofacial Pain. Wolters Kluwer Health Adis (ESP)

Research output: Chapter in Book/Report/Conference proceedingChapter

Facial Pain
Pain
Animal Models
Cancer Pain
Theoretical Models
13 Citations

In Vitro Analysis of Scaffold-free Prevascularized Microtissue Spheroids Containing Human Dental Pulp Cells and Endothelial Cells

Dissanayaka, W. L., Zhu, L., Hargreaves, K. M., Jin, L. & Zhang, C. May 1 2015 In : Journal of Endodontics. 41, 5, p. 663-670 8 p.

Research output: Contribution to journalArticle

Dental Pulp
Human Umbilical Vein Endothelial Cells
Endothelial Cells
Extracellular Matrix
Regeneration

Men with acute cholecystitis have higher tissue-based cytokine levels than women: A cross-sectional study

Fehrenbacher, J. C., Bingener, J., Aho, J. M., Wasky, P. R., Locke, E. E., Schwesinger, W. H., Van Sickle, K. R. & Hargreaves, K. M. Apr 1 2015 In : Chirurgia (Turin). 28, 2, p. 49-53 5 p.

Research output: Contribution to journalArticle

Acute Cholecystitis
Cross-Sectional Studies
Gallbladder
Cytokines
Extracellular Fluid
34 Citations

Persistent nociception triggered by nerve growth factor (NGF) is mediated by TRPV1 and oxidative mechanisms

Eskander, M. A., Ruparel, S., Green, D. P., Chen, P. B., Por, E. D., Jeske, N. A., Gao, X., Flores, E. R. & Hargreaves, K. M. Jun 3 2015 In : Journal of Neuroscience. 35, 22, p. 8593-8603 11 p.

Research output: Contribution to journalArticle

Nociception
Nerve Growth Factor
Hyperalgesia
Capsaicin
Hypersensitivity
6 Citations

Released lipids regulate Transient Receptor Potential Channel (TRP)-dependent oral cancer pain

Ruparel, S., Bendele, M., Wallace, A. & Green, D. May 26 2015 In : Molecular Pain. 11, 1, 30

Research output: Contribution to journalArticle

Transient Receptor Potential Channels
Mouth Neoplasms
Hyperalgesia
Lipids
Squamous Cell Carcinoma
1 Citations

Role of TRP ion channels in physiology and pathology introduction

Akopian, A. Nov 12 2015 (Accepted/In press) In : Seminars in Immunopathology.

Research output: Contribution to journalArticle

Ion Channels
Pathology
8 Citations

Temporal-controlled Dexamethasone Releasing Chitosan Nanoparticle System Enhances Odontogenic Differentiation of Stem Cells from Apical Papilla

Shrestha, S., Diogenes, A. & Kishen, A. Aug 1 2015 In : Journal of Endodontics. 41, 8, p. 1253-1258 6 p.

Research output: Contribution to journalArticle

Chitosan
Nanoparticles
Dexamethasone
Stem Cells
Odontoblasts
33 Citations

The interplay of dental pulp stem cells and endothelial cells in an injectable peptide hydrogel on angiogenesis and pulp regeneration in vivo

Dissanayaka, W. L., Hargreaves, K. M., Jin, L., Samaranayake, L. P. & Zhang, C. Feb 1 2015 In : Tissue Engineering - Part A. 21, 3-4, p. 550-563 14 p.

Research output: Contribution to journalArticle

Dental Pulp
Hydrogel
Endothelial cells
Stem cells
Hydrogels
2014
6 Citations
Estrogen Receptor alpha
Bradykinin
Sensory Receptor Cells
Nociception
Estrogen Receptors
12 Citations

A standardized novel method to measure radiographic root changes after endodontic therapy in immature teeth

Flake, N. M., Gibbs, J. L., Diogenes, A., Hargreaves, K. M. & Khan, A. A. Jan 2014 In : Journal of Endodontics. 40, 1, p. 46-50 5 p.

Research output: Contribution to journalArticle

Endodontics
Tooth Root
Tooth
Outcome Assessment (Health Care)
Nonvital Tooth
64 Citations

Concentration-dependent effect of sodium hypochlorite on stem cells of apical papilla survival and differentiation

Martin, D. E., De Almeida, J. F. A., Henry, M. A., Khaing, Z. Z., Schmidt, C. E., Teixeira, F. B. & Diogenes, A. Jan 2014 In : Journal of Endodontics. 40, 1, p. 51-55 5 p.

Research output: Contribution to journalArticle

Sodium Hypochlorite
Stem Cells
Survival
Edetic Acid
Endodontics
5 Citations

Direct effect of endodontic sealers on trigeminal neuronal activity

Ruparel, N. B., Ruparel, S. B., Chen, P. B., Ishikawa, B. & Diogenes, A. 2014 In : Journal of Endodontics. 40, 5, p. 683-687 5 p.

Research output: Contribution to journalArticle

Calcitonin Gene-Related Peptide
Endodontics
Zinc Oxide
Eugenol
Nociceptors
48 Citations

Effect of dentin conditioning with intracanal medicaments on survival of stem cells of apical papilla

Althumairy, R. I., Teixeira, F. B. & Diogenes, A. 2014 In : Journal of Endodontics. 40, 4, p. 521-525 5 p.

Research output: Contribution to journalArticle

Dentin
Ointments
Stem Cells
Anti-Bacterial Agents
Survival
51 Citations

Evaluation of triple antibiotic paste removal by different irrigation procedures

Berkhoff, J. A., Chen, P. B., Teixeira, F. B. & Diogenes, A. 2014 In : Journal of Endodontics. 40, 8, p. 1172-1177 6 p.

Research output: Contribution to journalArticle

Ointments
Dentin
Dental Pulp Cavity
Anti-Bacterial Agents
Calcium Hydroxide
20 Citations

Hypoxia modulates the differentiation potential of stem cells of the apical papilla

Vanacker, J., Viswanath, A., De Berdt, P., Everard, A., Cani, P. D., Bouzin, C., Feron, O., Diogenes, A., Leprince, J. G. & des Rieux, A. Sep 1 2014 In : Journal of endodontics. 40, 9, p. 1410-1418 9 p.

Research output: Contribution to journalArticle

Stem Cells
Vascular Endothelial Growth Factor B
Hypoxia
Up-Regulation
Neurotrophin 3
9 Citations
Translational Medical Research
Endodontics
Clinical Protocols
Research Personnel
Outcome Assessment (Health Care)
11 Citations

Prolactin receptor in regulation of neuronal excitability and channels

Patil, M. J., Henry, M. A. & Akopian, A. N. 2014 In : Channels. 8, 3, p. 193-202 10 p.

Research output: Contribution to journalArticle

Prolactin Receptors
Prolactin
Neurons
Maternal Behavior
Neurogenesis

Pulp Injury and Changing Trends in Treatment

Hargreaves, K. M., Diogenes, A. & Teixeira, F. B. Nov 13 2014 Stem Cell Biology and Tissue Engineering in Dental Sciences. Elsevier Inc., p. 397-404 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Periapical Periodontitis
Canals
Tissue engineering
Pulp
Tooth